The Conception Coast Region has been defined as an area stretching from the Santa Maria River watershed in the north to the Santa Clara River and Calleguas Creek watersheds in the south. The region includes all of Santa Barbara County, most of Ventura County, and small portions of San Luis Obispo, Kern, and Los Angeles Counties, as well as the Channel Islands, Santa Barbara Channel, and the coastal waters of the area.

The Regional Conservation Guide provides an overview of the requirements of the Conception Coast regional landscape for long-term ecological sustainability, and offers tools to guide community action towards achieving it.